MoD Health & Safety Handbook 
JSP 375 Vol 2 
LEAFLET 5 ANNEX K 
MANAGEMENT OF HAZARDOUS SUBSTANCES INC. LEAD & ASBESTOS 
CONTENTS 
Para 
  TOXICOLOGICAL 
SAFETY 
 1  Introduction 
 2  MoD 
position 
 4  Procedures 
TOXICOLOGICAL SAFETY 
INTRODUCTION 
1 
Even modest exposure to some chemicals can cause serious damage to health if continued over 
long periods without adequate precautions being taken. MOD sometimes develop and use new and 
novel chemical substances in its work, many of them in an unconventional way in R&D establishments 
and in factories, and sometimes little if anything is known about the harmful effects of these substances 
on people or the environment. There is a duty under the Health and Safety at Work etc Act 1974 
(HSWA) to ensure, so far as is reasonably practicable, that when use of such substances is being 
considered, the toxicological risks are assessed to establish a reasonable presumption of safety before 
human exposure occurs. 
MOD POSITION 
2 
Many MOD establishments and contractors are involved in dealing with toxicological hazards and 
discharging the obligations under the HSWA. In most cases, where the substance is well known and 
standards of contamination established, satisfactory control measures and working procedures can be 
readily set up to ensure safe conditions. 
3 
The growing public and political awareness of the health implications of exposure to chemical 
substances, and the specific obligations incorporated in the HSWA, have made it necessary to institute 
a formal system for ensuring that all potential requirements for toxicity tests are identified at the outset 
and channelled into a programme that uses the advice and expertise of CBDE to best effect. 
PROCEDURES 
4 
The general responsibility for safety lies with Directors and Heads of Establishments for all 
activities within their establishments and with project managers or integrated project team leaders for 
aspects relevant to their projects.  Where, however, questions of toxic hazard arise, it is particularly 
important that the scientists and project officers immediately concerned with the introduction of new 
substances or processes are aware of the potential dangers and draw them to the attention of the 
appropriate authorities through their IPTL in good time. The following systems, which in many ways 
formalise existing practice, will therefore operate: 
4.1 
All MOD scientists, project officers or IPTLs responsible for the use of existing substances 
that may pose a potential toxic hazard must ensure that the risks have been assessed and the 
conclusions of the assessment acted upon, in accordance with the requirements of the Control of 
Substances Hazardous to Health Regulations, seeking advise as necessary, 
Leaflet 5 Annex K 
October 2001 
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